5 1 月, 2023

逆势融资1亿+美元，这家创新药Biotech有何独特之处？

SHENZHEN, Jan 5, 2023 - (亚太商讯 via SEAPRWire.com) - 2016年启动的新一轮药政改革吹响了中国医药产业“由仿到创”升级的冲锋号角，也掀起了创新药产业发展的第一波浪潮，大量的资本和人才被吸引涌入这个新兴的创新产业，通过license in、fast follow、me too/better等性价比相对较高的研发模式为整个行业带来了充足的创新药项目，明显改善了中国民众的创新药可及性。全球创新药项目投融资概况（截至2022年11月30日，来源：医药魔方PharmaInvest）经过大约5年的快速成长，中国创新药产业在2021年初来到了新的节点。愈发激烈的项目同质化内卷竞争让更多人开始反思过去几年的发展模式，医药二级市场Biotech新股的连续破发给过去的模式按下了暂停键。2021年6月CDE发布的《以临床价值为导向的抗肿瘤药物临床研发指导原则（征求意见稿）》文件也被视为产业发展节奏转变的指挥棒，带动中国创新药产业进入了第二波浪潮。2022年的一级市场创新药项目融资金额的整体规模只有2021年的一半，二级市场医药板块的投资热情也未恢复。不过对于整个行业来讲，这或许也是下一波创新药浪潮到来之前最好的内功修炼时间。同时，也有越来越多积极的事情正在发生，向我们传递着行业回暖的信号。1月5日，创新药公司君圣泰宣布完成1.07亿美元的C轮和C+轮融资，这是近两年来比较罕见的高额融资。君圣泰这轮融资的领投机构是国家开发银行全资子公司国开金融和广东国资设立的广东中医药大基金以及广州的越秀产业基金，所募资金将主要用于加速推进2型糖尿病（T2DM）、非酒精性脂肪性肝炎（NASH）、严重高甘油三酯血症（SHTG）、原发性硬化性胆管炎（PSC）等适应症的临床全球开发，同时展开其他候选产品的临床及临床前研究。这样一笔大额融资在当下尤显珍贵。那么君圣泰究竟有何独特之处吸引投资人？君圣泰对当前的创新药开发有何见解？我们也可以通过与君圣泰创始人刘利平博士的交流内容中略窥一二。核心产品HTD1801瞄准糖尿病合并脂肪肝的临床治疗空白从管线来看，君圣泰的研发方向主要集中在消化和代谢疾病领域，核心产品HTD1801拟开发多项适应症，目前基本处于II期临床阶段。其中推进最快也颇为特别的一项适应症是T2DM；在开发过程中，君圣泰将格外关注HTD1801对T2DM合并非酒精性脂肪肝（NAFLD）患者群体的临床获益。如果拆开来看，T2DM市场早已是一片“红海”，全球已上市的T2DM药物超过130种，但没有一款药物能充分满足T2DM合并NAFLD患者的综合性治疗需求。在谈到为何选择关注T2DM合并NAFLD这一患者群体的临床需求时，刘利平博士指出：“我国有1亿多糖尿病患者、1-2亿脂肪肝患者，而同时患有糖尿病和脂肪肝的患者超过7000万。这两种疾病合并发生的情况非常常见。肝脏是主要的糖代谢器官，糖尿病和脂肪肝互为因果，有很强的双向关系，导致同时患有两种疾病的患者控糖更难，肝病也更容易进展到脂肪性肝炎或肝硬化。糖尿病领域已经有很多药物上市，比如二甲双胍和胰岛素可以控制血糖，胰岛素的长期使用可能会加重脂肪肝，二甲双胍对于脂肪肝疗效有待验证。对于糖尿病合并脂肪肝患者来说，他们肯定希望一个有效药物可以综合性解决问题。但是现有的T2DM疗法无法满足需求，所以我们觉得需要开发一款first in class（FIC）疗法来填补治疗空白。”HTD1801的分子设计也是瞄准了临床上的这一需求。据刘利平博士介绍，HTD1801是基于两种天然产物小檗碱和熊去氧胆酸构建的新分子实体。小檗碱是一种天然生物碱，传统药理研究认为其具有显著的抗炎、抗菌、抗病毒作用。现代研究显示，小檗碱可通过多种机制发挥改善代谢、保护肝脏等作用；而熊去氧胆酸也是有漫长人用历史的天然产物，传统医学经验和现代科学研究结果显示，熊去氧胆酸具有利胆、保肝、抗炎抗氧化应激、改善代谢等作用。HTD1801同时具有小檗碱和熊去氧胆酸，实现了1+1>2的协同治疗效果，目前已在多项临床试验中证明了其卓越的应用潜力。“HTD1801的设计还有另一个考虑。代谢和消化疾病通常都不是单因素疾病，如果能做一个具备多种药理活性的药，既可以减少患者的用药负担又可以满足他们的临床需求。”刘利平博士说道。HTD1801目前推进最快的适应症是T2DM，临床II期基本完成，计划今年进入III期临床。HTD1801的适应症选择和开发进度也暗合了刘利平博士分享的君圣泰产品开发策略的3条标准：1）找到真正的临床需求，这是生物医药公司未来在商业上立于不败之地的根基。2）在配备资源的时候判断哪一个适应症或者哪一个产品能够尽快地把开发周期走完，且具备成为“重磅炸弹”的潜力，然后想尽一切办法加快商业化速度。3）考虑多个适应症之间的“协同”作用。FIC药物开发成败的关键：平衡创新性与成药性当前新药同质化竞争激烈，开发FIC药物确实是更具差异化的选择，但是FIC药物同时也面临分子成药性的不明确性风险。因此，平衡创新性与成药性是FIC新药开发必须考虑的问题。君圣泰对新药研发风险评估有自己的一套标准。刘利平博士将其总结为4个英文字母——STEP，S代表safety，T代表tolerability，E代表efficacy，P代表price。当满足以上4个标准时，一个新分子才具备转化为候选药物的资格。HTD1801就是一个融合上述理念的代表性案例。自2014年Intercept在JP摩根大会上公布奥贝胆酸治疗NASH的II期结果后，这个药物就一炮而红。但是刘利平博士从数据中敏锐地发现，奥贝胆酸会导致患者的低密度脂蛋白胆固醇（LDL-C）上升，这会给患者带来潜在的心脑血管疾病风险。2020年6月，奥贝胆酸NASH适应症的NDA申请收到了FDA的完整回应函（complete response letter，CRL），给出的理由也印证了这一点：相对于治疗风险，治疗收益不够明确和充足。刘利平博士将“肝脏获益+心血管获益”作为肝病药物开发的疗效金标准。基于此，刘利平博士关注到小檗碱和熊去氧胆酸的药理活性十分丰富，但二者单独使用时皆存在一定局限性。联想到一些协同疗法（复方、双抗、多抗等）的设计理念，刘利平博士设想将两个分子融合成一个全新分子或许会带来意想不到的效果。由此诞生了HTD1801。“单独来看，小檗碱和熊去氧胆酸是两个活性和安全性经过验证的分子，不存在成药性的问题。合并来看，HTD1801又是一个具有更优越特性的全新分子，具备创新性。这样子，我们就解决了创新性与成药性平衡的问题。”立足源头的创新，始于起点的国际化2022年初几款国产新药的“出海”失败给中国创新药的国际化上了宝贵一课。国际化布局如何进行也是业内近两年思考讨论最多的问题之一。君圣泰对此也有一些自己的理解。首先，君圣泰在创立之初就坚持“做走向全球的原创产品”的理念。“开发具有国际创新性的产品的优势很明显，可以在全球范围内享受专利保护，拥有全球市场。这就意味着，当你做了一个全新药物的时候，只考虑国内市场会限制它的临床价值和市场空间，所以我们必须考虑在海内外同步推进临床开发，这也是为了在最大程度上满足全球患者的治疗需求。”刘利平博士说道。其次，君圣泰组建了一个强大的国际化管理团队，其中包括负责奥贝胆酸开发的Leigh MacConell博士和美国肝病研究学会（AASLD）前主席Adrian Di Bisceglie博士。刘利平博士表示：“在着手开发HTD1801之前，我们对慢病领域排名靠前的KOL进行了仔细研究，最后邀请了这些顶级专家作我们的临床研究者，同时招聘经验丰富的高管加入我们的团队。一方面是考虑到这些专家参与过多款产品从临床前到上市的开发过程，他们拥有非常丰富的研发经验；另一方面是考虑到国际专家具备丰富的海外资源，包括从研发到监管，可以为我们产品的在国外上市提供很大帮助。”关于如何提高“出海”成功率，刘利平博士还有一些其它看法。“第一，一定要跟监管部门保持有效沟通。举个容易理解的例子。假设今天我请了一些客人到家里吃饭，如果我没有问他们的喜好就自顾自做了一堆菜，可能会导致有些菜根本没人吃的问题。但如果我提前跟每一个人沟通他们的喜好，并且在做菜的过程中时不时确认是否符合客人的口味，那最后吃饭的时候大家都会很满意。所以我觉得，一定要跟监管部门保持有效沟通。这在团队中也是一样。”“第二，合理设计临床方案。在做临床方案设计的时候一定不是闭门造车的，入组/排除标准、终点预定、统计学分析方案等等都特别重要。”“第三，有效运营，包括临床运营和资金管理。确保患者入组在既定时间完成、确保数据的质量这些很重要，合理地运用资金推进临床试验开展对产品的开发也是很重要的。”“第四，TPP原则——targeted、product、profile。就是要明白你做的产品是一个什么样的产品，你想满足什么样的需要，你在药品说明书上是写的什么东西。有了这样的一个思考的时候，你在做方案设计，包括整个临床开发计划的时候，就会时刻都兼顾到你的终点是什么样子。而且TPP是随着时间的推进在变化的，因为你对产品的认知也会不停地做调整，但是你不能说我没有目标，边做边决定。你脑子里必须先有一个目标，边做边调整，保证大方向是对的。”小结对于中国的创新药企业来说，2022年是充满反省的一年。“资本寒冬”和疫情反复的外部环境让创新药开发变得举步维艰。在这种情况下，我们不得不思考一个问题：如何才能在变幻莫测的大环境下保证公司的长期发展？或许，答案很简单，“一切研发以患者需求为中心”，这十二个字足矣。正如刘利平博士所说，“凡是为满足患者真正需求而产出的药品，都可以称之为新药，而这样的药是未来能让你在商业上立于不败之地的最初的原点。”文章来源：医药魔方 Copyright 2023 亚太商讯. All rights reserved. (via SEAPRWire)

6 12 月, 2022

Series of “Overseas Talents’ China Visit to Shenzhen” Events Successfully Held

SHENZHEN, CHINA, Dec 6, 2022 - (ACN Newswire via SEAPRWire.com) - A series of "Overseas Talents' China Visit to Shenzhen" events were successfully held in Guangming district, Shenzhen from November 21 to 22. The events were co-organized by Shenzhen Center for International Exchange of Personnel. The events are hosted by the China Association for International Exchange of Personnel, the Shenzhen Science and Technology Innovation Commission, the Communist Party of China Guangming District Committee, and the Shenzhen Guangming District People's Government.Presented by Guangming District Talent Work Bureau and Guangming District High-level Talent Service Center and co-organized by Shenzhen International Personnel Exchange Center, the series of events feature visits and exchanges by foreign experts, a forum for global experts and an exchange activity for Chinese and foreign guests named "The Night of Guangming", to name a few.The foreign experts symposium under "Overseas Talents' China Visit to Shenzhen" was held via video link in Beijing and Shenzhen on the afternoon of November 21.Li Xin, Deputy Director-General of the Department of Foreign Expert Services of China's Ministry of Science and Technology, Xia Bing, Deputy Director of China Association for International Exchange of Personnel, Cheng Buyi, Member of the Standing Committee of the CPC Shenzhen Municipal Committee and Minister of the Organization Department, Cai Ying, Secretary of the Guangming District Party Committee, attended the meeting and delivered speeches through online and offline channels. Qiu Haohang, Deputy Secretary of the Guangming District Party Committee and Chief of Guangming District, presided over the meeting.The events gathered academicians and experts from six countries, including the US, the UK, Italy, Germany, France and Cuba, putting the spotlight on topics such as original innovation breakthroughs, scientific research and economic development, talents opening up, and talent highland construction.Answering the requirements of "facing the world's scientific and technological frontier, facing the main economic battlefield, facing major national strategic needs and facing people's life and health", the series of activities gave Shenzhen a thorough examination and offered suggestions based on the city's industrial development characteristics and its environment for innovation and entrepreneurship.Aimed at tapping into the innovation plateau with talents, the events help the Guangming district to speed up the construction of a world-class science city and to become a representative and pioneer for Shenzhen's participation in future technology competitions.During the events, foreign experts also visited Shenzhen Engineering Biological Industry Innovation Center, Feiyada Museum, Shenzhen Bay Laboratory, Dadingling Greenway -- Hongqiao Park and other research institutes and key enterprises. They listened to the introduction of institutions, and exchanged with scientific and technological personnel, laying the foundation for future cooperation.Media contactWang Chan, Shenzhen Center for International Exchange of PersonnelEmail: wangchan@ciep.gov.cnTel: 0755-81707961; 0755-81773121Website: http://www.ciep.gov.cn/SOURCE: Shenzhen Center for International Exchange of Personnel Copyright 2022 ACN Newswire. All rights reserved. (via SEAPRWire)

28 11 月, 2022

Shenzhen Global Marine Forum to Focus on Ocean Leadership, Sustainability

SHENZHEN, November 28, 2022 – (SEAPRWire) – The Shenzhen Global Marine Economy Forum 2022, the executive strategy session of the high-powered China Marine Economy Expo, opened Thursday with the aim of further developing China’s booming “Blue Economy” and boosting global exchange and cooperation.This year’s marine forum, titled “Leadership for the Sustainable Expansion of the Marine Economy,” will bring together dozens of senior government officials, top business executives, leaders of global organizations, academic experts and renowned thought leaders. The hybrid event will also be live streamed on the internet. The two-day forum, which concludes Friday, will feature nine panel discussions on hot-button issues, such as marine technology, industry, shipping, transportation and governance. The goal of the forum, as in years past, is to promote dialogue and knowledge exchanges between the world’s ocean cities and to accelerate the development of marine partnerships. “The Shenzhen Global Marine Economy Forum is a bridge for exchanges and communication between Shenzhen and the rest of the world,” said Huang Min, deputy mayor of Shenzhen Municipality, during the opening ceremony. “It is also an important platform for pooling global wisdom and discussing cooperation and development. We hope you will use this platform to focus on the development of the marine industry and technological innovations in marine science, ecology and governance.” Huang Min pointed out that in 2021, the Shenzhen’s economy was third largest of all cities in China, fourth in Asia, and the tenth largest in the world. China’s marine economy was worth more than 9 trillion yuan (about USD $1.41 trillion) in 2021, an annual increase of 8.3%, and represented 8% of the country’s GDP growth in 2021. This relatively small percentage, however, does not fully reflect the crucial role that maritime industries – such as shipping, fishing, offshore energy, coastal tourism, and biotech – play in the overall economy and in people’s daily lives.As noted in the previous Marine Forums, there is no way to overestimate the potential of the Blue Economy, for China and the world. Official estimates have the global marine economy reaching at least USD $3 trillion US dollars by 2030.“We look forward to seeing people from around the world join hands to open up new prospects for marine cities and together achieve new developments in the marine economy,” said Huang Min, the deputy mayor. The Shenzhen Global Marine Forum is hosted by the China Oceanic Development Foundation, Global Ocean Capital Promotion Council of Shenzhen and the Yantian District People’s Government of Shenzhen.The forum was organized by Shenzhen SEZ Construction and Development Group Co.,Ltd, and will be produced by Smadja and Smadja Strategic Advisory of Switzerland, and Beijing Cexing Technology Co.,Ltd. The article is provided by a third-party content provider. SEAPRWire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Any questions, please contact cs/at/SEAPRWire.com Sectors: Top Story, Daily News SEA PRWire: PR distribution in Southeast Asia (Hong Kong: AsiaExcite, EastMud; AsiaEase; Singapore: SEAChronicle, VOASG; NetDace; Thailand: SEAsiabiz, AccessTH; Indonesia: SEATribune, DailyBerita; Philippines: SEATickers, PHNotes; Malaysia: SEANewswire, KULPR; Vietnam: SEANewsDesk, PostVN)

7 3 月, 2022

EC Healthcare Included as an Eligible Stock of the Shenzhen – Hong Kong Stock Connect

HONG KONG, Mar 7, 2022 - (ACN Newswire via SEAPRWire.com) - EC Healthcare (the "Company", which together with its subsidiaries is referred to as the "Group", SEHK stock code: 2138), the largest non-hospital medical group in Hong Kong*, is pleased to announce that the Company has been included as an eligible stock of Shenzhen-Hong Kong Stock Connect, with effect from March 7, 2022, pursuant to the Announcement on Adjustment of the Stock List of Hong Kong Stock Connect issued by the Shenzhen Stock Exchange on March 7, 2022. Mainland investors can directly trade the Company's stock after the Company is included as an eligible stock of the Shenzhen - Hong Kong stock connect.The Company believes the inclusion of the shares of the Company in the trading mechanism of Shenzhen-Hong Kong Stock Connect demonstrates market recognition of the Company's investment value and growth prospects. The Company believes the inclusion will allow the Company to access a broader investor base in Mainland China and further expand the shareholder base of the Company, increase the trading liquidity of the shares of the Company, support the sustainable growth of the Company in the long term.The Company would like to thank the shareholders and investors of the Company for their continued support. The Company will continue to strive to develop its business to consolidate the healthcare market and create value for its shareholders.About EC Healthcare EC Healthcare is Hong Kong's largest non-hospital medical service provider*, leveraging its core businesses of preventive and precision medicine, and committed to developing medical artificial intelligence by integrating its multi-disciplinary medical services. The move, which is supported by the Group's high-end branding and quality customer services, is aimed at offering customers safe and effective healthcare and medical services with professionalism. The Group is a constituent stock of the Hang Seng Composite Index and the MSCI Hong Kong Small Cap Index.The Group principally engages in the provision of one-stop medical and health care services in Greater China. The Group provides a full range of services and products under its well-known brands, including those of its one-stop aesthetic medical solutions provider DR REBORN which has ranked first in Hong Kong by sales for years, primary care clinics jointly established with Tencent Doctorwork, chiropractic services centre SPINE Central, New York Spine and Physiotherapy Center NYMG, health management centre re:HEALTH, a vaccine centre Hong Kong Professional Vaccine HKPV, a comprehensive dental centre UMH DENTAL CARE, a diagnostic and imaging centre HKAI, an oncology treatment centre reVIVE, a day procedure centre HKMED, a specialty clinic SPECIALISTS CENTRAL and NEW MEDICAL CENTER, obstetrics and gynaecology specialist ZENITH MEDICAL CENTER AND PRENATAL DIAGNOSIS CENTRE, specialists central, a paediatric center PRIME CARE, cardiology center HONG KONG INTERNATIONAL CARDIOLOGY CENTER, PathLab Medical Laboratories, a professional hair care center HAIR FOREST, Ophthalmology Center VIVID EYE and EC Veterinary Hospital and Imaging Center.*According to independent research conducted by Frost and Sullivan in terms of revenue in 2019 and 2020For further information, please contact: iPR Ogilvy Limited Callis Lau / Lorraine Luk / Charmaine IpTel: (852) 2136 6952 / 2169 0467 / 3920 7649Fax: (852) 3170 6606 Email: ech@iprogilvy.com Copyright 2022 ACN Newswire. All rights reserved. (via SEAPRWire)

20 12 月, 2021

Shenzhen Global Investment Promotion Conference 2021 held December 15

Themed ‘New Era, New Journey — Invest in Shenzhen, Build a Winning Future’ SHENZHEN, CHINA, Dec 16, 2021 – (ACN Newswire) – Shenzhen this week hosted the 2021 Shenzhen Global Investment Promotion Conference, to attract and focus greater international investment. The Conference highlighted the development directions of Shenzhen’s strategic emerging industries and those of the future as well as key industries and projects in each district, while gathering global investors and quality resources to further develop Shenzhen as a premier choice for global investment. 2021 Shenzhen Global Investment Promotion Conference was hosted by the Shenzhen Municipal People’s Government and jointly organized by the Commerce Bureau of Shenzhen Municipality, Information Office of Shenzhen Municipal People’s Government, and Foreign Affairs Office of Shenzhen Municipal People’s Government. Themed “New Era, New Journey — Invest in Shenzhen, Build a Winning Future”, the Conference was held on December 15 at Wuzhou Guest House, Shenzhen, showcasing to global investors the economic vitality, innovative impetus, city charm and investment potential. Representatives from the VP level and above from Fortune Global 500 and China’s Top 500 corporations, large SOEs, leading private enterprises, listed companies, and unicorn companies were invited to participate at the Conference. Invitations also went to those in charge of international organizations such as foreign embassies and consulates in China, major business associations and others, all companies and institutions having actively signed up for the Conference. Due to the cross-border travel limits, some senior executives of multinational enterprises, international institutions and representatives of major cities extended video-linked congratulations to Shenzhen and the Conference. The Conference was organized in the format of a “1+12+N” series of events. In other words, it consisted of 1 main event, 12 district-level investment promotion conferences, and N overseas parallel sessions and industrial investment promotion activities, forming a complete series of investment promotion campaigns. In addition to the main session in Shenzhen, 12 overseas parallel sessions were staged in 12 cities across five continents, including Los Angeles, New York, Toronto and Sao Paulo in the Americas, London, Paris, and Brussels in Europe, Hong Kong and Tokyo in Asia, Sydney and Brisbane in Oceania, as well as Johannesburg, South Africa, promoting the city brand “Invest in Shenzhen, Build a Winning Future” to all parts of the world. This was the third time that Shenzhen has hosted the Global Investment Promotion Conference since 2019. At the Conference, the International Headquarters Enterprise, Investment Advisor of Shenzhen, and Outstanding Registered Enterprise were awarded, and shared in the “Shenzhen Moments” of investment promotion. A number of major projects were also signed, demonstrating the attractiveness and innovation of Shenzhen as well as the confidence of investors from around the globe in the future development of Shenzhen and its districts. Media Contact:Commerce Bureau of Shenzhen MunicipalityWang YandanE: swj@commerce.sz.gov.cnU: http://commerce.sz.gov.cn

14 9 月, 2021

Tennis: 2021 WTA Finals moved from Shenzhen to Guadalajara

FLORIDA (REUTERS) - The season-ending WTA Finals will be held in Guadalajara, Mexico, instead of Shenzhen, China, this year and will begin on Nov 8, the WTA Tour said on Monday (Sept 13). The WTA Finals, contested by the world's top eight singles players and eight doubles teams, was cancelled last year due to the Covid-19 pandemic. In July, the WTA removed the Asian swing of tournaments from its calendar for a second successive year due to the pandemic, with only the WTA Finals' fate uncertain. "We are excited to bring our showpiece tournament to the exciting and vibrant city of Guadalajara in this unique year," WTA chairman and CEO Steve Simon said in a statement. "I would also like to express my gratitude to the Gemdale Corporation in Shenzhen for their cooperation and resilience, and we look forward to returning in 2022 to enjoy the WTA Finals over the next decade." The WTA Finals is set to return to Shenzhen from 2022 and the Chinese city will host every edition until 2030. The annual showpiece event had a prize purse of US$14 million (S$18.8 million) in 2019 when it was played in Shenzhen for the first time after ending a five-year run in Singapore. More on this topic Related Story Tennis: ATP and WTA inch closer to merger after combining marketing ops Related Story Tennis: Serena Williams crashes out of WTA top 10

10 6 月, 2021

HKTDC launches GoGBA one-stop platform

HONG KONG, Jun 10, 2021 - (ACN Newswire via SEAPRWire.com) - The Hong Kong Trade Development Council (HKTDC) has announced the launch of the GoGBA one-stop platform, a new business support programme that helps companies access the Guangdong-Hong Kong-Macao Greater Bay Area (GBA). Consisting of digital information and business tools, advisory services and training as well as promotional and networking activities, the GoGBA one-stop platform offers multi-faceted business support online and offline.The GoGBA one-stop platform was launched at this morning's online ceremony in Hong Kong and Shenzhen. The officiating guests in Hong Kong included (from L) Erick Tsang, Secretary for Constitutional and Mainland Affairs of the HKSAR; Dr Peter K N Lam, Chairman of the HKTDC; Carrie Lam, Chief Executive of the HKSAR; Edward Yau, Secretary for Commerce and Economic Development of the HKSAR; and Margaret Fong, HKTDC Executive Director.GoGBA WeChat mini programme (QR Code)At today's launch event, which took place via a virtual link between Hong Kong and Shenzhen, Carrie Lam, Chief Executive of the Hong Kong Special Administrative Region (HKSAR), and Qin Weizhong, Deputy Secretary of Shenzhen Municipal Committee of the Communist Party of China and Mayor of Shenzhen Municipal People's Government, officially launched the GoGBA WeChat mini programme - a digital information and business tool - and the HKTDC GBA Centre located at the HKTDC's Shenzhen office. Several memorandums of understanding (MoUs) were also signed with the Leading Group Office of Guangdong on Construction of Guangdong-Hongkong-Macao Greater Bay Area, the China Council for the Promotion of International Trade Shenzhen Municipal Committee, the People's Government of Shenzhen Futian District and five cities and districts in the GBA (Qianhai in Shenzhen, Nansha in Guangzhou, Hengqin in Zhuhai, Dongguan and Zhongshan), to expand the network of support for Hong Kong companies. After the ceremony, two webinars were held where companies that are already operating successfully in the GBA shared their business insights on how to succeed in the region.Dr Peter K N Lam, Chairman of the HKTDC, said: "The GBA offers huge opportunities for businesses from Hong Kong and around the world. Our GoGBA WeChat mini programme is a useful digital tool to complement our physical support centres in Hong Kong and Shenzhen, and other parts of the GBA through our partners. As more and more businesses look for prospects in the GBA, the HKTDC is here to help."One-stop platform covers three major service areasIn line with the HKSAR Chief Executive's 2020 policy address, the GoGBA one-stop platform aims to help Hong Kong small and medium-sized enterprises (SMEs) tap into the GBA with three major support components:1. Digital tool for cross-border businessThe GoGBA digital platform, which consists of the GoGBA WeChat mini programme digital messaging platform, comes into service effective today. The GoGBA digital platform is run in collaboration with the government offices of Guangdong province and municipal governments in the GBA, providing important information on the region including updates on policies and subsidies, listings of related business and trade organisations, regional guides, and information on GBA government services and applications. It also offers practical tools such as weather forecasts, cross-border transportation information, interactive maps, details of public services, and income tax reminders. Media friends can scan the WeChat QR code included in this press release to download the GoGBA digital platform.2. Advisory services and trainingThe HKTDC's Shenzhen office has set up the HKTDC GBA Centre to strengthen its support to SMEs interested in exploring the GBA market. Together with the HKTDC SME Centre in Hong Kong, the centres will organise a series of seminars and workshops, sharing sessions and advisory activities in group or individual formats, equipping companies with the practical knowledge and skillsets needed to succeed in the GBA.The MoUs signed today will see the introduction of GoGBA Business Support Centres in Shenzhen (Qianhai), Guangzhou (Nansha), Zhuhai (Hengqin), Dongguan and Zhongshan. The HKTDC targets to introduce the centres in all nine mainland cities in the GBA, establishing a comprehensive support network that can connect companies with partners and consultants from across the GBA.In addition, the HKTDC's Transformation Sandbox (T-box) programme will extend its services from Hong Kong to Shenzhen and other cities in the GBA. Together with the Digital Academy and E-Tailing Academy, the HKTDC will provide advisory workshops related to e-commerce and digital business as well as marketing solutions and other digital platforms.3. HKTDC online and offline activitiesThe HKTDC has utilised various digital technologies to organise exhibitions and conferences, and will continue to plan and organise business missions and networking events by adopting a new "digital and physical" format for its major events and activities. It will also continue to enhance the hktdc.com Sourcing platform. The "Guangdong-Hong Kong Co-operation Week" will be held with the People's Government of Guangdong Province in December to promote Hong Kong products and services through flagship promotional events - SmartHK in Guangzhou and ChicHK in Shenzhen.The HKTDC will continue its outreach efforts to help Hong Kong and overseas companies, and enterprises from other GBA cities, to establish connections, providing business matching sessions and advice on seeking business opportunities. The Council is currently planning to organise a wide range of activities in the mainland, including exhibitions and conferences, to help Hong Kong enterprises promote their products and services, explore business opportunities in GBA cities and gain practical experience at the same time.GoGBA WeChat mini programme (QR Code) https://tinyurl.com/5pnps82rHKTDC SME CentreTel: +852 1830 668Fax: +852 3693 4938E-mail: smecentre@hktdc.orgAddress: Ground Level, Hong Kong Convention and Exhibition Centre, 1 Expo Drive, Wan Chai, Hong KongHKTDC GBA CentreTel: +86-0755-82280112Fax: +86-0755-82280114E-mail: shenzhen.office@hktdc.orgAddress: Unit 2405-06, Jindi Centre, Shennan Road 2007, Futian District, ShenzhenHong Kong and overseas companies share key to success in GBARepresentatives from Hong Kong and overseas companies gathered at this morning's launch event to share their success stories in capturing opportunities in mainland GBA cities through Hong Kong. Sharing their experiences in two separate sessions were Yan Lau, General Manager of Dongguan Dailywin Watch; Tommy Cheng, Founder and CEO of MY Super eCommerce Company; Jason Choi, Founder of DimYeah Studio & EGGY; Dawn Chui, General Manager - Pacific Rim of ORCA Asia; Joe Wan, CEO of Tricor Hong Kong; and Jefrey Hironaka Santo, Managing Director for Asia of Mundial.ORCA is a Canadian company specialising in technology solutions for the treatment of food waste. Dawn Chui, General Manager - Pacific Rim of ORCA, said the pandemic has accelerated awareness of the need for food waste treatment in Hong Kong, and that an increasing number of hotels, campuses and restaurants are interested in their solutions. She said the company is optimistic about the mainland market. "The National 14th Five-Year Plan mentioned the issue of food waste management so we see great potential in venturing into this market. Hong Kong is the perfect springboard to Mainland China, with its free flow of capital very beneficial to corporate finance and one of the factors that encouraged us to establish a Hong Kong branch."Yan Lau, General Manager of Dongguan Dailywin Watch, said the company set up its factory in Dongguan in the 1980s. Now, its Hong Kong headquarters is responsible for import, export, accounting and auditing functions, while the design, manufacturing and sales activities are carried out in Dongguan. Mr Lau said the company has put a big effort into building its own brand and last year launched the SAGA Moon Mars series to celebrate the achievements of the mainland's aerospace industry along with Dailywin's own achievements. During the pandemic, the company has shifted the focus to its online business and domestic sales, adopting new strategies such as e-commerce livestreaming with influencers and deploying new e-commerce and social e-commerce retail models. These new strategies have proved beneficial in helping the company's expansion in the mainland market.Photo download: https://bit.ly/3gbhI1GAbout HKTDC The Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Follow us on Twitter @hktdc and LinkedIn.Media enquiries:HKTDC Communications & Public Affairs DepartmentSnowy Chan, Tel: +852 2584 4525, Email: snowy.sn.chan@hktdc.orgAngel Tang, Tel: +852 2584 4544, Email: angel.hc.tang@hktdc.org Copyright 2021 ACN Newswire. All rights reserved. (via SEAPRWire)

10 5 月, 2021

Yeahka’s Associated Company Fushi to Acquire 60% of Shenzhen Zhizhanggui Cloud Service

HONG KONG, May 10, 2021 - (ACN Newswire via SEAPRWire.com) - Yeahka Limited (Stock Code: 9923), a leading payment-based technology platform in China, announced that Shenzhen Zhizhanggui Cloud Service Co., Ltd. ("Zhizhanggui") and Shenzhen Leshou Cloud Technology Co., Ltd. ("Leshou"), both indirect wholly-owned subsidiaries of Yeahka, have entered into a non-legally binding memorandum of understanding with Fushi Technology (Shenzhen) Co., Ltd. ("Fushi"), an associated company of Yeahka which the Company holds approximately 47.58% equity interests in aggregate through its indirect subsidiaries, in relation to the potential disposal of 60% Zhizhanggui's equity interests by Leshou to Fushi (the "Potential Disposal"). The Potential Disposal equates to a consideration of approximately RMB201.9 million, based on a valuation of Zhizhanggui of approximately RMB336.5 million.The Potential Disposal, if consummated, is expected to realize gains before tax from asset disposals of over RMB200 million for the Company. Fushi is an important member of Yeahka's ecosystem, expanding its merchant base and providing services to more than 420,000 merchants with peak transaction counts of over 8,380,000 as of March 31, 2021.Through the acquisition of Zhizhanggui, Fushi will obtain a cornerstone "hardware+software" standardized infrastructure and further accelerate its open-SaaS strategy by integrating the established SaaS modules to offline merchants.Not only does the historical investment in Zhizhanggui yield significant returns, as the single largest shareholder in Fushi, Yeahka is able to focus on more asset-light, industry agnostic SaaS solutions such as "Yuehuiquan", a blockchain's underlying technology-based solution that enables merchants to operate their private domain traffic. Jointly with Fushi, Yeahka will continue to strengthen its SaaS portfolio and remain committed to establishing a commercial digitalized ecosystem.About YEAHKA LIMITED (9923.HK)Yeahka Limited is a leading payment-based technology platform in China providing payment and technology-enabled business services to merchants and consumers. The Company was listed on The Stock Exchange of Hong Kong Limited (the "Stock Exchange") in June 2020 under the stock code "09923.HK". The Company's value proposition is to create a commercial digitalized ecosystem that enables seamless, convenient and reliable payment transactions between merchants and consumers and further offer a rich variety of technology-enabled business services, including (i) merchant SaaS products, which help customers improve their operational efficiency, (ii) precision marketing services, allowing customers to effectively reach their target markets, and (iii) fintech services, which cater to customers' diverse financial needs. Copyright 2021 ACN Newswire. All rights reserved. (via SEAPRWire)

9 3 月, 2021

淘屏成立区块链事业群任命邓琳㬢为事业群总裁

SHENZHEN, CHINA, Mar 9, 2021 - (亚太商讯 via SEAPRWire.com) - 淘屏有限公司（纳斯达克： TAOP，简称“淘屏”或“公司”）今日宣布成立区块链事业群，致力于区块链和数字资产业务的发展，并任命邓琳㬢女士为区块链事业群总裁。邓女士在区块链领域拥有多年行业经验，曾在自己创立的新块（北京）科技有限公司任职，负责比特币矿场和区块链运营。在加入淘屏前，邓女士在Polar Bear Mining担任COO，负责建设10MW加拿大阿尔伯塔天然气电矿场和矿机货源采购。邓女士还具备10年以上的互联网从业经验，曾先后在新浪、MagentJoy、informatree等公司任职。淘屏董事局主席兼首席执行官林江怀先生表示：“区块链事业群的成立和邓女士的任命标志着淘屏区块链和数字资产业务的正式启动，邓女士在区块链和互联网行业的丰富经验将有助于推动公司新的发展战略。我们欢迎邓女士担任这一新角色，成为淘屏的重要一员。” Copyright 2021 亚太商讯. All rights reserved. (via SEAPRWire)

4 12 月, 2020

Shenzhen Global Investment Promotion Conference to be held December 8

SHENZHEN, CHINA, Dec 4, 2020 - (ACN Newswire) - The 2020 Shenzhen Global Investment Promotion Conference is sponsored by the Shenzhen Municipal Government and undertaken by the Shenzhen Municipal Bureau of Commerce. It will officially start in Wuzhou Guest House on December 8th.Since the beginning of this year, Shenzhen has actively overcome the impact of COVID-19, improved the business environment and promoted the projects of domestic and foreign investment enterprises. Shenzhen also plans to consolidate its position as a target of foreign investment by providing an attractive package of incentive policies, including land, talents, industry, technology and business environment."The conference is an extremely important platform to showcase the ambition of the city, a pilot demonstration area of socialism with Chinese characteristics, and to give further impetus to its trajectory," commented a spokesman of the city's Commerce Bureau.The conference, to be held annually, is bound to become a must-attend attraction for global investors seeking to tap into new opportunities arising from China's reform and opening up.According to the official, despite the ongoing global COVID-19 pandemic, cyberspace has facilitated efforts which, after months of hard work, has resulted in a group of investment projects which will be signed on the site.The conference is attracting senior executives from around 300 companies and institutes, including 65 Fortune Global 500 companies.Besides the main venue in Shenzhen, parallel sessions in eight cities across five continents, including New York, London, Tokyo, and Sydney will be held, truly a testament to the impact Shenzhen has on the world stage.After 40-years of development, official figures continue to show the vanguard of China's reform and opening-up remains one of the country's top investment destinations with the city utilizing $7 billion foreign investment in the first 10 months of this year alone, up 7.58 percent from a year before.According to officials, the city's already impressive investment environment will be even further improved.The Commerce Bureau is accelerating legislation on the promotion of foreign investment, which will offer better protect of legal rights and interests of foreign investors.Furthermore, according to the city's Planning and Natural Resources Bureau, the city government will ensure ample supply of land space for industrial use and lower land costs for investors.And on top of even that, the city's HR and Social Security Bureau tells us that overseas professionals in Shenzhen, who fall in to the categories of high-end talents and urgently needed talents, will be able to enjoy a subsidy on personal income tax equivalent to that in the neighboring Hong Kong SAR.Media Contact:Sherry Tang, swj@commerce.sz.gov.cnCommerce Bureau of Shenzhen MunicipalitySource:http://www.sz.gov.cn/cn/xxgk/zfxxgj/zwdt/content/post_8314390.html Copyright 2020 ACN Newswire. All rights reserved. www.acnnewswire.com